Diagnosing Sorbitol Intolerance

The symptoms of Sorbitol Intolerance are unspecific; they correspond not only to the symptoms of Fructose Malabsorption and Lactose Intolerance, but also to those of Histamine Intolerance, Celiac Disease, Wheat Sensitivity, Intolerance to FODMAPs, and sometimes even to the symptoms of food allergies.

A patient's symptom diary may be helpful to the physician. If sufferers avoid sorbitol for a few days and feel better during this time, it may be evidence in support of a sorbitol intolerance diagnosis.

Hydrogen breath test, as with Lactose- and Fructose Intolerance

If the patient is suspected of having a Sorbitol Intolerance beyond the normal level, a physician can perform a hydrogen breath test. The patient usually drinks 10 grams of sorbitol on an empty stomach. This dose is lower than that of lactose or fructose in the tests for Lactose Intolerance and Fructose Malabsorption because humans basically only tolerate small amounts of sorbitol.

If the patient suffers from a Sorbitol Intolerance, the absorbed sorbitol is not transported away in the small intestine, but moves into the large intestine. There, it is first converted to fructose and then further split. When the fructose is metabolized, hydrogen is produced and released by the body through the breath - the higher hydrogen content in the breath thus indicates a Sorbitol Intolerance. The principle of the test is the same as in the tests for Fructose Malabsorption or Lactose Intolerance. The range between normal and pathological in the sorbitol test is significantly narrower, however. A sorbitol test would catch most people, even the perfectly healthy.

Please see also:

What is Sorbitol Intolerance?

Symptoms of Sorbitol Intolerance

Therapy for Sorbitol Intolerance